The triatomic oxygen molecule ozone (O3) is becoming increasingly important as a therapy not only in the environmental field, but also increasingly in medicine. Although the origins of ozone therapy date back to the time of World War I, when an ozone-oxygen mixture was used to improve wound healing processes, it soon fell into oblivion due to lack of technology. After the technical requirements were significantly improved by ozone-resistant materials in the early 50s, the German physicist Hänsler succeeded in the construction of an ozone generator, which also and above all the accurate metering of the ozone-oxygen mixture made possible. The generation of ozone is carried out by electrical discharges. Thus, ozone therapy has been reactivated and, especially in the last 20 years of the past century, it has been gradually advanced so that today it is regarded as a clinically and biochemically sound treatment method. Generally, ozone is produced for medical purposes from pure oxygen and always applied in the form of an ozone-oxygen mixture. The ozone therapy is subdivided into the following three main groups of therapy, which differ in particular by the respectively used ozone concentration:
1. Systemic treatment with up to 65 μg / ml ozone
2. local treatment of poorly healing wounds and proctitis (40 - 70 μg / ml ozone)
3. local treatment of superinfected wounds and colitis (70 - 100 μg / ml ozone)
For medical ozone-oxygen mixtures, oxygen serves not only as a raw material for ozone generation but also as an "ozone solvent" in the range of 0.05 to a maximum of 5 % by volume of ozone. This corresponds to the concentration range used in practice of 1 to 100 μg / ml of ozone.
In contrast to the technical ozone, medical-grade oxygen, which is commonly used in medicine, is produced by silent electric discharge in the total absence of nitrogen (due to the risk of nitric oxide formation). With a half-life of 55 minutes in an ozone-resistant 50 ml disposable syringe, the medical ozone must be prepared at the place of use and delivered to its application.
Due to a strong absorption band in the near ultraviolet range with a maximum at 254 nm, a very accurate determination of the concentration of ozone can be done by photometric means. This ensures safe therapeutic handling. Ozone is primarily a strong oxidizer. The associated germicidal effect is mainly used in local treatments. At lower ozone concentrations (systemic treatment) restorative effects (improvement of the peripheral oxygen supply, activation of the immune system in the foreground.
The systemic ozone therapy works basically with low ozone concentration works basically with low ozone concentrations. There is first a blood sample, then the defined enrichment of the blood with an ozone-oxygen mixture and finally the return of the treated blood in the body. Systemic ozone therapy can be performed in two different forms:
1. small ozone autologous blood treatment (KEB)
2. large ozone autologous blood treatment (GEB)B)
In the case of GEB, the normobaric and hyperbaric form of therapy used to be different. Today, the GEB is usually performed hyperbaric: ozone enrichment and reinfusion are under increased pressure, and the entire treatment process is automated device. The decision as to whether KEB or GEB will be used depends on the disease.
Here, only a small amount (2 - 4 ml) of blood is taken, enriched with ozone (2-5%) and then returned by intramuscular injection. The exact treatment parameters depend on the clinical picture. The KEB is used in its main characteristic as nonspecific stimulus therapy especially for acne vulgaris, allergies (especially skin, mucous membranes), bronchial asthma, mucous membrane, large intestinal slag, circulatory disorders, furunculosis, cancer treatments for immune activation, liver disease, liver detoxification and psoriasis.
In the hyperbaric large autologous blood treatment, about 220 ml of blood are taken from the vein to the patient and, after ozone enrichment, are pressure-assisted in a closed, sterile system. During enrichment, an ozone-oxygen mixture adjusted exactly in its concentration perfuses the blood, with the ozone reacting in seconds while the oxygen accumulates over the blood. During retransfusion, no O2 or O3 molecules enter the bloodstream, but only the reaction products between ozone and the cellular blood components, which now have their therapeutic effect in the body.
There are many thousands of successful treatments in this therapy, and with modern technology and strict quality assurance regulations, the treatment risk is extremely low. Especially in the following complexes of complaints is the large ozone autologous blood treatment used: circulatory disorders, hearing loss, viral diseases (eg, hepatitis, herpes simplex, zoster), immunodeficiency, migraine, dizziness, sleep disorders, arteriosclerosis, increased blood lipid levels.
Treatment with GEB is not recommended if hyperthyroidism or sickle cell anemia are present.
As life expectancy increases, tissue alterations, inferior oxygen uptake via the lungs, decreased body defenses and cancer significantly increase.
Per therapy, usually 8 to 10 individual treatments are required. The treatment lasts about 15 to 30 minutes and will be arranged by appointment. In a preliminary examination at the beginning of the therapy, the exact procedure is determined individually depending on the indication. This applies in particular to the decision as to whether the small or large ozone autologous blood treatment is required, the total number of treatments and their treatment interval, the amount of extracorporeal blood to be treated and the ozone concentration to be used. Remember: for 40 years, ozone therapy has been carried out worldwide with great success. The pleasant effect of the therapy is already experienced after a few applications.